Reaction: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol
- in pathway: Synthesis of pyrophosphates in the cytosol
Inositoltetrakisphosphate 1-kinase (ITPK1) phosphorylates inositol 3,4,5,6-tetrakisphosphate (I(3,4,5,6)P4) to inositol 1,3,4,5,6-pentakisphosphate (I(1,3,4,5,6)P5) (Yang & Shears 2000).
Reaction - small molecule participants:
ADP [cytosol]
I(1,3,4,5,6)P5 [cytosol]
I(3,4,5,6)P4 [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-1855162
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Reaction input - small molecules:
1D-myo-inositol 3,4,5,6-tetrakisphosphate(8-)
ATP(4-)
Reaction output - small molecules:
ADP(3-)
myo-inositol 1,3,4,5,6-pentakisphosphate(10-)
Reactome.org link: R-HSA-1855162