Reaction: I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol
- in pathway: Synthesis of IP2, IP, and Ins in the cytosol
Inositol polyphosphate 1-phosphatase (INPP1) dephosphorylates inositol 1,4-bisphosphate (I(1,4)P2) to inositol 4-phosphate (I4P) (York et al. 1993).
Reaction - small molecule participants:
Pi [cytosol]
I4P [cytosol]
H2O [cytosol]
I(1,4)P2 [cytosol]
Reactome.org reaction link: R-HSA-1855208
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Reaction input - small molecules:
water
1D-myo-inositol 1,4-bisphosphate
Reaction output - small molecules:
hydrogenphosphate
1D-myo-inositol 4-phosphate
Reactome.org link: R-HSA-1855208