Reaction: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol
- in pathway: Synthesis of IP2, IP, and Ins in the cytosol
Inositol polyphosphate 1-phosphatase (INPP1) dephosphorylates inositol 1,3,4-trisphosphate (I(1,3,4)P3) to inositol 3,4-bisphosphate (I(3,4)P2) (York et al. 1993).
Reaction - small molecule participants:
Pi [cytosol]
I(3,4)P2 [cytosol]
H2O [cytosol]
I(1,3,4)P3 [cytosol]
Reactome.org reaction link: R-HSA-1855232
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Reaction input - small molecules:
water
1D-myo-inositol 1,3,4-trisphosphate(6-)
Reaction output - small molecules:
hydrogenphosphate
1D-myo-inositol 3,4-bisphosphate
Reactome.org link: R-HSA-1855232