Reaction: Digestion of triacylglycerols by extracellular PTL:colipase
- in pathway: Digestion of dietary lipid
Pancreatic lipase catalyzes the hydrolysis of extracellular triacylglycerols to yield diacylglycerols and long-chain fatty acids. The enzyme is active only when complexed with colipase protein and plays a major role in the digestion of dietary triacylglycerols in the small intestine (Carriere et al. 2000; Giller et al. 1992).
Reaction - small molecule participants:
LCFAs [extracellular region]
DAGs [extracellular region]
H2O [extracellular region]
TAGs [extracellular region]
Reactome.org reaction link: R-HSA-192422
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Reaction input - small molecules:
water
triglyceride
Reaction output - small molecules:
long-chain fatty acid
diglyceride
Reactome.org link: R-HSA-192422