Reaction: Digestion of diacylglycerols by extracellular PTL:colipase
- in pathway: Digestion of dietary lipid
Pancreatic lipase catalyzes the hydrolysis of extracellular dicylglycerols to yield monoacylglycerols and long-chain fatty acids. The enzyme is active only when complexed with colipase protein and plays a major role in the digestion of dietary diacylglycerols in the small intestine (Carriere et al. 2000; Giller et al. 1992).
Reaction - small molecule participants:
MAG [extracellular region]
LCFAs [extracellular region]
H2O [extracellular region]
DAGs [extracellular region]
Reactome.org reaction link: R-HSA-192434
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Reaction input - small molecules:
water
diglyceride
Reaction output - small molecules:
monoacylglycerol
long-chain fatty acid
Reactome.org link: R-HSA-192434