Reaction: 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol
5beta-cholestan-3alpha, 7alpha-diol, NADPH + H+, and O2 react to form 5beta-cholestan-3alpha, 7alpha, 26-triol + NADP+ + H2O. This reaction occurs in the mitochondrial matrix, catalyzed by CYP27A1.
Reaction - small molecule participants:
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,26-triol [mitochondrial matrix]
H2O [mitochondrial matrix]
5beta-cholestan-3alpha, 7alpha-diol [mitochondrial matrix]
O2 [mitochondrial matrix]
H+ [mitochondrial matrix]
NADPH [mitochondrial matrix]
Reactome.org reaction link: R-HSA-193393
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Reaction input - small molecules:
5beta-cholestane-3alpha,7alpha-diol
dioxygen
hydron
NADPH
Reaction output - small molecules:
NADP(+)
5beta-cholestane-3alpha,7alpha,26-triol
water
Reactome.org link: R-HSA-193393