Reaction: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al
5beta-cholestan-3alpha, 7alpha, 26-triol and NADP+ react to form 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al and NADPH + H+. This oxidation reaction occurs in the mitochondrial matrix, catalyzed by CYP27A1.
Reaction - small molecule participants:
3alpha,7alpha-dihydroxy-5beta-cholestan-26-al [mitochondrial matrix]
H+ [mitochondrial matrix]
NADPH [mitochondrial matrix]
NADP+ [mitochondrial matrix]
5beta-cholestan-3alpha,7alpha,26-triol [mitochondrial matrix]
Reactome.org reaction link: R-HSA-193497
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Reaction input - small molecules:
NADP(+)
5beta-cholestane-3alpha,7alpha,26-triol
Reaction output - small molecules:
3alpha,7alpha-dihydroxy-5beta-cholestan-26-al
hydron
NADPH
Reactome.org link: R-HSA-193497