Reaction: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA
25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to form (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA. This reaction, catalyzed by the peroxisomal D-bifunctional enzyme (Huyghe et al. 2006), occurs in the peroxisomal matrix.
Reaction - small molecule participants:
3,7,24THCA-CoA [peroxisomal matrix]
H2O [peroxisomal matrix]
25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA [peroxisomal matrix]
Reactome.org reaction link: R-HSA-193535
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Reaction input - small molecules:
water
3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA
Reaction output - small molecules:
3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA
Reactome.org link: R-HSA-193535