Reaction: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA

- in pathway: Synthesis of bile acids and bile salts via 24-hydroxycholesterol
The isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA, catalyzed by 2-methylacyl-CoA racemase, occurs in the peroxisomal matrix.
Reaction - small molecule participants:
(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA [peroxisomal matrix]
25(R) TetraHCA-CoA [peroxisomal matrix]
Reactome.org reaction link: R-HSA-193763

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Reaction input - small molecules:
3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA
ChEBI:27458
Reaction output - small molecules:
(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA
ChEBI:52050
Reactome.org link: R-HSA-193763