Reaction: 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol
3,7,24THCA (3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate) is translocated from the mitochondrial matrix to the cytosol. The transporter that mediates its passage across the inner mitochondrial membrane has not been identified (Russell 2003). VLCS (SLC27A2), one of the enzymes that catalyzes CoA conjugation of 3,7,24THCA, may also be present in peroxisomes, and Mihalik et al. (2002) have hypothesized that 3,7,24THCA could be translocated unchanged from the mitochondrial matrix to the peroxisomal matrix and undergo conjugation there.
Reaction - small molecule participants:
3,7,24THCA [cytosol]
3,7,24THCA [mitochondrial matrix]
Reactome.org reaction link: R-HSA-193786
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Reaction input - small molecules:
3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oic acid
Reaction output - small molecules:
3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oic acid
Reactome.org link: R-HSA-193786