Reaction: COASY transfers an adenylyl group from ATP to PPANT
- in pathway: Coenzyme A biosynthesis
The adenylyl transferase activity of bifunctional coenzyme A synthase (COASY) catalyzes the transfer of an adenylyl group from ATP to pantetheinephosphate (PPANT) to form dephospho-Coenzyme A (DP-CoA) (Daugherty et al. 2002). The enzyme is associated with the mitochondrial outer membrane (Zhyvoloup et al. 2003).
Reaction - small molecule participants:
PPi [cytosol]
DP-CoA [cytosol]
PPANT [cytosol]
H+ [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-196754
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Reaction input - small molecules:
D-pantetheine 4'-phosphate(2-)
hydron
ATP(4-)
Reaction output - small molecules:
diphosphate(3-)
3'-dephospho-CoA(2-)
Reactome.org link: R-HSA-196754