Reaction: COASY phosphorylates DP-CoA
- in pathway: Coenzyme A biosynthesis
The kinase activity of CoA synthase (COASY) catalyzes the phosphorylation of dephospho-CoA to form Coenzyme A (CoA-SH). The enzyme is located in the mitochondrial outer membrane (Daugherty et al. 2002; Zhyvoloup et al. 2003).
Reaction - small molecule participants:
H+ [cytosol]
ADP [cytosol]
CoA-SH [cytosol]
DP-CoA [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-196773
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Reaction input - small molecules:
3'-dephospho-CoA(2-)
ATP(4-)
Reaction output - small molecules:
hydron
ADP(3-)
coenzyme A(4-)
Reactome.org link: R-HSA-196773