Reaction: NAMPT transfers PRIB to NAM to form NAMN
- in pathway: Nicotinamide salvaging
Nicotinamide phosphoribosyltransferase (NamPRT) catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide D-ribonucleotide (NMN), an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
Reaction - small molecule participants:
PPi [cytosol]
NAMN [cytosol]
PRPP [cytosol]
NAM [cytosol]
Reactome.org reaction link: R-HSA-197250
======
Reaction input - small molecules:
5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-)
nicotinamide
Reaction output - small molecules:
diphosphate(3-)
nicotinic acid D-ribonucleotide
Reactome.org link: R-HSA-197250