Reaction: TRKA phosphorylates IRS
- in pathway: PI3K/AKT activation
IRS1 and IRS2 are tyrosine phosphorylated at multiple YXXM motifs by the active TRKA kinase (Miranda et al.2001).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-198295
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-198295