Reaction: AKT phosphorylates CREB1
- in pathway: AKT phosphorylates targets in the nucleus
AKT phosphorylates CREB (cAMP response element-binding protein) at serine 133 and activates gene expression via a CREB-dependent mechanism, thus promoting cell survival.
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-199298
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Reaction input - small molecules:
ATP(4-)
ATP(4-)
Reaction output - small molecules:
ADP(3-)
ADP(3-)
Reactome.org link: R-HSA-199298