Reaction: Cytosolic folate export across the plasma membrane
- in pathway: Metabolism of folate and pterines
SLC46A1 protein in the plasma membrane mediates the reversible transport of folate between the extracellular space and the cytosol. Retention of folate within the cell is dependent on polyglutamate addition (Qiu et al. 2006; Chen et al. 1996).
Reaction - small molecule participants:
FOLA [extracellular region]
FOLA [cytosol]
Reactome.org reaction link: R-HSA-200646
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Reaction input - small molecules:
folic acid
Reaction output - small molecules:
folic acid
Reactome.org link: R-HSA-200646