Reaction: Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)
- in pathway: Metabolism of Angiotensinogen to Angiotensins
Chymase hydrolyzes angiotensin-(1-10) (angiotensin) to yield angiotensin-(1-8) (angiotensin II) at a higher rate than does angiotensin-converting enzyme (Reilly et al. 1982, Urata et al. 1990, Caughey et al. 2000, Richard et al. 2001).
Reaction - small molecule participants:
H2O [extracellular region]
Reactome.org reaction link: R-HSA-2022383
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-2022383