Reaction: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)
- in pathway: Metabolism of Angiotensinogen to Angiotensins
Cathepsin G hydrolyzes angiotensin-(1-10) (angiotensin I) to yield angiotensin-(1-8) (angiotensin II) (Reilly et al. 1982, Owen and Campbell 1998, Raymond et al. 2010). Cathepsin bound to the plasma membrane of neutrophils has a higher activity than does soluble cathepsin G (Owen and Campbell 1998).
Reaction - small molecule participants:
H2O [extracellular region]
Reactome.org reaction link: R-HSA-2022411
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-2022411