Reaction: Phosphorylation of MOB1A and B by p-STK4(MST1)/N
- in pathway: Signaling by Hippo
Cytosolic MOB1A and MOB1B are phosphorylated by phospho-STK4(MST1)/N (Graves et al. 1998; Lee et al. 2001). Threonine residues 12 and 35 have been experimentally identifed as the targets of MOB1A phosphorylation; the homologous residues of MOB1B are inferred likewise to be targets.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-2028670
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-2028670