Reaction: Conversion of PA into DAG by PAP-1
- in pathway: Role of phospholipids in phagocytosis
Phosphatidic acid phosphatase (PAP) bound to the plasma membrane catalyzes the dephosphorylation of phosphatidic acid (PA), yielding diacylglycerol (DAG) and inorganic phosphate. In humans, Diacylglycerol pyrophosphate (DPPL1 and DPPL2) perform this reaction.
Reaction - small molecule participants:
Pi [cytosol]
DAGs [plasma membrane]
H2O [cytosol]
PA [plasma membrane]
Reactome.org reaction link: R-HSA-2029468
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Reaction input - small molecules:
water
phosphatidate(2-)
Reaction output - small molecules:
hydrogenphosphate
diglyceride
Reactome.org link: R-HSA-2029468