Reaction: palmitoylation of eNOS
- in pathway: eNOS activation
DHHC-21 is a Golgi-localized acyl transferase that palmitoylates eNOS, which targets eNOS to plasmalemmal caveolae. Localization to this microdomain is likely to optimize eNOS activation and the extracellular release of nitric oxide.
Reaction - small molecule participants:
PALM-CoA [cytosol]
Reactome.org reaction link: R-HSA-203567
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Reaction input - small molecules:
palmitoyl-CoA(4-)
Reaction output - small molecules:
Reactome.org link: R-HSA-203567