Reaction: Vesicle budding
- in pathway: COPII-mediated vesicle transport
Once loaded the vesicles become fully sculpted, pinch off from the ER and bud into the cytosol. Budding depends on SAR1:GTPase activity and likely releases the SEC16 complex. SAR1:GTPase activity may result in partial uncoating of the emerging vesicle, allowing SEC23 to be exposed for subsequent TRAPPCII binding.
Reaction - small molecule participants:
Pi [cytosol]
Reactome.org reaction link: R-HSA-203973
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Reaction input - small molecules:
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-203973