Reaction: Translocation of tetracosapentaenoyl-CoA to peroxisomes
- in pathway: Linoleic acid (LA) metabolism
Prior to this reaction all the enzymes involved in the desaturation and elongation of linoleic acid are located in the ER, but for this last step tetracosapentaenoyl-CoA must be transferred to the peroxisomes for partial beta-oxidation to docosapentaenoyl-CoA (DPA-CoA, 4,7,10,13,16-22:5(n-6)) (Su et al. 2001).
Reaction - small molecule participants:
Pi [endoplasmic reticulum membrane]
TPA-CoA [peroxisomal matrix]
ADP [endoplasmic reticulum membrane]
TPA-CoA [endoplasmic reticulum lumen]
ATP [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-2046093
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Reaction input - small molecules:
(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA
ATP(4-)
Reaction output - small molecules:
hydrogenphosphate
(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA
ADP(3-)
Reactome.org link: R-HSA-2046093