Reaction: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA
- in pathway: Linoleic acid (LA) metabolism
Tetracosatetraenoyl-CoA is further desaturated by delta 6-desaturase (FADS2) to tetracosapentaenoyl-CoA (TPA-CoA, 6,9,12,15,18-24:5(n-6)).
Reaction - small molecule participants:
NAD+ [endoplasmic reticulum lumen]
H2O [endoplasmic reticulum lumen]
TPA-CoA [endoplasmic reticulum lumen]
O2 [endoplasmic reticulum lumen]
TTA-CoA [endoplasmic reticulum lumen]
NADH [endoplasmic reticulum lumen]
Reactome.org reaction link: R-HSA-2046097
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Reaction input - small molecules:
dioxygen
(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA
NADH(2-)
Reaction output - small molecules:
NAD(1-)
water
(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA
Reactome.org link: R-HSA-2046097