Reaction: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG
- in pathway: Keratan sulfate biosynthesis
Carbohydrate sulfotransferases 2, 5 and 6 (CHST2, 5 and 6) catalyze the transfer of sulfate to position 6 of non-reducing ends of N-acetylglucosamine (GlcNAc) residues within keratan-like molecules (Sakaguchi et al. 2000, Lee et al. 1999, Akama et al. 2002). Keratan(4)-PG represents keratan before sulfation has occurred.
Reaction - small molecule participants:
PAP [Golgi lumen]
PAPS [Golgi lumen]
Reactome.org reaction link: R-HSA-2046222
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Reaction input - small molecules:
3'-phosphonato-5'-adenylyl sulfate(4-)
Reaction output - small molecules:
adenosine 3',5'-bismonophosphate(4-)
Reactome.org link: R-HSA-2046222