Reaction: NRAGE activates JNK
- in pathway: NRAGE signals death through JNK
The NGF:p75:NRAGE complex promotes threonine and tyrosine phosphorylation, and activation of JNK, by an unknown mechanism.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-205132
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-205132