Reaction: Two DITs combine to form thyroxine
- in pathway: Thyroxine biosynthesis
Thyroxine (T4) can be formed by the combination of two diiodotyrosines. The hormone thyrotropin can stimulate the production of T3 and T4.
Reaction - small molecule participants:
T4 [extracellular region]
L-Ala [extracellular region]
DIT [extracellular region]
Reactome.org reaction link: R-HSA-209840
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Reaction input - small molecules:
3,5-diiodo-L-tyrosinate(1-)
Reaction output - small molecules:
L-thyroxine
L-alanine zwitterion
Reactome.org link: R-HSA-209840