Reaction: Collagen type IV networks bind integrins alpha1beta1, alpha2beta1
- in pathway: Integrin cell surface interactions
The collagen receptors integrin alpha2beta1 and alpha1beta1 bind collagen types I-IV (Tulla et al. 2001). Integrin alpha1beta1 binds to collagen type IV and VI with higher affinity than to types I-III, whereas alpha2beta1 has a higher affinity for collagen types I-III than for type IV (Tulla et al. 2001).
Reaction - small molecule participants:
Mg2+ [extracellular region]
Reactome.org reaction link: R-HSA-216040
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Reaction input - small molecules:
magnesium(2+)
Reaction output - small molecules:
Reactome.org link: R-HSA-216040