Reaction: Collagen type I binds integrin alpha11beta1
- in pathway: Integrin cell surface interactions
The integrin alpha11beta1 along with alpha1beta1, alpha2beta1 and alpha10beta1 are referred to as a collagen receptor subgroup of the integrin family. Integrin alpha11beta1 binds preferentially to the fibril-forming collagen types I and II, binding to type III is weaker and collagens IV and VI are poor ligands (Zhang et al. 2003).
Reaction - small molecule participants:
Mg2+ [extracellular region]
Reactome.org reaction link: R-HSA-216045
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Reaction input - small molecules:
magnesium(2+)
Reaction output - small molecules:
Reactome.org link: R-HSA-216045