Reaction: PGA2 is dehydrated to 15d-PGA2
- in pathway: Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
The non-enzymatic dehydration of prostaglandin A2 (PGA2) into 15-deoxy prostaglandin A2 (15d-PGA2) which occurs in mice (Petrova et al. 1999) is inferred in humans.
Reaction - small molecule participants:
H2O [cytosol]
15d-PGA2 [cytosol]
PGA2 [cytosol]
Reactome.org reaction link: R-HSA-2161668
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Reaction input - small molecules:
prostaglandin A2
Reaction output - small molecules:
water
15-deoxy-Delta(12,14)-prostaglandin A2
Reactome.org link: R-HSA-2161668