Reaction: PGD2 is dehydrated to PGJ2
- in pathway: Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Analogous to prostaglandin E2 (PGE2), dehydration of the prostaglandin D2 (PGD2) prostane ring forms prostaglandin J2 (PGJ2) (Monneret et al. 2002).
Reaction - small molecule participants:
H2O [endoplasmic reticulum lumen]
PGJ2 [endoplasmic reticulum lumen]
PGD2 [endoplasmic reticulum lumen]
Reactome.org reaction link: R-HSA-2161733
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Reaction input - small molecules:
prostaglandin D2
Reaction output - small molecules:
water
prostaglandin J2
Reactome.org link: R-HSA-2161733