Reaction: LXA4 is oxidised to 15k-LXA4 by HPGD
- in pathway: Synthesis of Lipoxins (LX)
15-Hydroxyprostaglandin dehydrogenase (HPGD) converts lipoxin A4 (LXA4) to 15-oxo lipoxin A4 aka 15-keto-LXA4 (15k-LXA4) (Clish et al. 2000).
Reaction - small molecule participants:
H+ [cytosol]
15k-LXA4 [cytosol]
NADH [cytosol]
LXA4 [cytosol]
NAD+ [cytosol]
Reactome.org reaction link: R-HSA-2161779
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Reaction input - small molecules:
lipoxin A4
NAD(1-)
Reaction output - small molecules:
hydron
15-oxolipoxin A4
NADH(2-)
Reactome.org link: R-HSA-2161779