Reaction: 15S-HETE is oxidised to 15-oxoETE by 15-HEDH
- in pathway: Synthesis of 15-eicosatetraenoic acid derivatives
A 15-hydroxy-eicosatetraenoic acid dehydrogenase (15-HEDH) oxidises 15S-hydroxyeicosatetraenoic acid (15S-HETE) to 15-oxo-eicosatetraenoic acid (15-oxoETE) (Gulliksson et al. 2007). The actual human 15-HEDH has yet to be cloned.
Reaction - small molecule participants:
H+ [cytosol]
15-oxoETE [cytosol]
15S-HETE [cytosol]
Reactome.org reaction link: R-HSA-2161789
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Reaction input - small molecules:
15(S)-HETE
Reaction output - small molecules:
hydron
15-oxo-ETE
Reactome.org link: R-HSA-2161789