Reaction: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)
Cytochrome P450s 1A1 (CYP1A1), 1A2 (CYP1A2), and 1B1 (CYP1B1) convert arachidonic acid to 16-, 17-, and 18-hydroxyeicosatetraenoic acids (16-, 17-, and 18-HETEs) (Choudhary et al. 2004).
Reaction - small molecule participants:
H2O [endoplasmic reticulum lumen]
NADP+ [endoplasmic reticulum lumen]
O2 [endoplasmic reticulum lumen]
H+ [endoplasmic reticulum lumen]
AA [endoplasmic reticulum lumen]
NADPH [endoplasmic reticulum lumen]
Reactome.org reaction link: R-HSA-2161795
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Reaction input - small molecules:
dioxygen
hydron
arachidonate
NADPH
Reaction output - small molecules:
water
NADP(+)
Reactome.org link: R-HSA-2161795