Reaction: HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH
- in pathway: Synthesis of Hepoxilins (HX) and Trioxilins (TrX)
The epoxy moiety of hepoxilin A3 (HXA3) and B3 (HXB3) is labile and can be hydrolysed either by a hepoxilin specific epoxide hydrolase (HXEH) or in acidic aqueous solution to form the corresponding diol metabolites trioxilin A3 (TrXA3) and B3 (TrXB3) (Anton et al. 1995, Anton et al. 1998, Pace-Asciak et al. 1983, Pace-Asciak & Lee 1989).
Reaction - small molecule participants:
H2O [cytosol]
Reactome.org reaction link: R-HSA-2161949
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-2161949