Reaction: MHDB is decarboxylated to DMPhOH by MHDB decarboxylase
- in pathway: Ubiquinol biosynthesis
3-methoxy-4-hydroxy-5-decaprenylbenzoic acid (MHDB) is enzymatically decarboxylated to form 2-methoxy-6-decaprenylphenol (DMPhOH). At the present time the enzyme identity is unknown but is thought to be a member of the COQ family. This reaction is inferred from the equivalent reaction in yeast (Casey & Threlfall 1978, Goewert et al. 1981).
Reaction - small molecule participants:
CO2 [mitochondrial matrix]
DMPhOH [mitochondrial matrix]
MHDB [mitochondrial matrix]
Reactome.org reaction link: R-HSA-2162195
======
Reaction input - small molecules:
3-decaprenyl-4-hydroxy-5-methoxybenzoic acid
Reaction output - small molecules:
carbon dioxide
2-decaprenyl-6-methoxyphenol
Reactome.org link: R-HSA-2162195