Reaction: The single sugars GlcA and GlcNAc translocate from the lysosome to the cytosol
- in pathway: Hyaluronan uptake and degradation
Glucuronate and N-acetylglucosamine exit the lysosome into the cytosol, ready for reuse in GAG biosynthesis. The mechanism of translocation is unknown (for reviews see Stern 2004, Stern 2003).
Reaction - small molecule participants:
GlcA [cytosol]
GlcNAc [cytosol]
GlcNAc [lysosomal lumen]
GlcA [lysosomal lumen]
Reactome.org reaction link: R-HSA-2162229
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Reaction input - small molecules:
aldehydo-N-acetyl-D-glucosamine
D-glucuronic acid
Reaction output - small molecules:
D-glucuronate
aldehydo-N-acetyl-D-glucosamine
Reactome.org link: R-HSA-2162229