Reaction: FPP and IPPP are combined into all-E-10PrP2 by PDSS1/2 tetramer
- in pathway: Ubiquinol biosynthesis
The polyprenyl diphosphate synthase consists of a tetramer comprising two units of decaprenyl-diphosphate synthase subunit 1 (PDSS1) and two units of decaprenyl-diphosphate synthase subunit 2 (PDSS2). It catalyses the combination of 2-trans,6-trans-farnesyl diphosphate (FPP) with isopentenyl diphosphate (IPPP) to form the polyisoprenoid tail all-trans-decaprenyl diphosphate (all-E-10PrP2) (Saiki et al. 2005, Tekle et al. 2008).
Reaction - small molecule participants:
PPi [mitochondrial matrix]
all-E-10PrP2 [mitochondrial matrix]
FPP [mitochondrial matrix]
IPPP [mitochondrial matrix]
Reactome.org reaction link: R-HSA-2162253
======
Reaction input - small molecules:
2-trans,6-trans-farnesyl diphosphate
isopentenyl diphosphate
Reaction output - small molecules:
diphosphate(3-)
all-trans-decaprenyl diphosphate
Reactome.org link: R-HSA-2162253