Reaction: Truncated Alpha-1-Microglobulin binds heme
- in pathway: Scavenging of heme from plasma
Truncated Alpha-1-Microglobulin binds heme b and then degrades heme b by an unknown mechanism (Allhorn et al. 2002). The crystal structure of the untruncated Alpha1-Microglobulin:heme complex indicates that each Alpha1-Microglobulin molecule binds 2 heme molecules and the Alpha1-Microglobulin molecules trimerize (Siebel et al. 2012).
Reaction - small molecule participants:
heme b [extracellular region]
Reactome.org reaction link: R-HSA-2168881
======
Reaction input - small molecules:
heme b
Reaction output - small molecules:
Reactome.org link: R-HSA-2168881