Reaction: RALA exchanges GDP for GTP
- in pathway: Translocation of SLC2A4 (GLUT4) to the plasma membrane
RALA releases GDP and binds GTP, producing the active form of RALA. The reaction is accelerated by guanine nucleotide exchange factors (GEFs) and opposed by GTPase-activating proteins (GAPs) which enhance the conversion of RALA:GTP back to RALA:GDP by activating the GTPase activity of RALA.
Reaction - small molecule participants:
GDP [cytoplasmic vesicle membrane]
GTP [cytoplasmic vesicle membrane]
Reactome.org reaction link: R-HSA-2255342
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Reaction input - small molecules:
GTP
Reaction output - small molecules:
GDP
Reactome.org link: R-HSA-2255342