Reaction: Formation of hydroxyallysine by LOX
- in pathway: Crosslinking of collagen fibrils
Hydroxylysines residues can be converted to hydroxyallysines by lysyl oxidase. In this representative reaction a single hydroxylysine residue in each collagen chain is shown as converted to hydroxyallysine (Pinnell et al. 1968, Siegel 1979).
Reaction - small molecule participants:
NH3 [extracellular region]
H2O2 [extracellular region]
H2O [extracellular region]
O2 [extracellular region]
Reactome.org reaction link: R-HSA-2395340
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Reaction input - small molecules:
water
dioxygen
Reaction output - small molecules:
ammonia
hydrogen peroxide
Reactome.org link: R-HSA-2395340