Reaction: AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40)
- in pathway: Constitutive Signaling by AKT1 E17K in Cancer
AKT1 E17K gain-of-function mutant is expected to phosphorylate AKT1S1 (PRAS40), like the wild-type AKT (Kovacina et al. 2003), but this has not been experimentally tested.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-2399977
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-2399977