Reaction: HSC cytosolic atROL translocates to extracellular region
- in pathway: Retinoid metabolism and transport
Once hydrolysed from all-trans-retinyl esters (atREs), all-trans-retinol (atROL) can either be esterified for storage or secreted into the bloodstream for transport to target tissues/organs (Kanai et al. 1968). The mechanism of secretion/efflux is currently unknown.
Reaction - small molecule participants:
atROL [extracellular region]
atROL [cytosol]
Reactome.org reaction link: R-HSA-2404139
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Reaction input - small molecules:
all-trans-retinol
Reaction output - small molecules:
all-trans-retinol
Reactome.org link: R-HSA-2404139