Reaction: tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer

- in pathway: Selenocysteine synthesis
The synthetic cycle of selenocysteine (Sec) synthesis starts with misacylation (serylation) of the cognate transfer RNA (tRNA) for Sec, tRNASec, with serine (Ser) by Serine--tRNA ligase (SARS) homodimer. The structural homology of tRNASec and tRNASer enables SARS to form Ser-tRNASec (Vincent et al. 1997, Amberg et al. 1996, Heckl et al. 1998).
Reaction - small molecule participants:
PPi [cytosol]
AMP [cytosol]
ATP [cytosol]
L-Ser [cytosol]
Reactome.org reaction link: R-HSA-2408526

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Reaction input - small molecules:
ATP(4-)
ChEBI:30616
L-serine zwitterion
ChEBI:33384
Reaction output - small molecules:
diphosphate(3-)
ChEBI:33019
adenosine 5'-monophosphate(2-)
ChEBI:456215
Reactome.org link: R-HSA-2408526