Reaction: Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer
- in pathway: Selenocysteine synthesis
O-phosphoseryl-tRNA(Sec) selenium transferase (SEPSECS) tetramer catalyses the transformation of phosphoserine (Sep) into selenocysteine (Sec) by using selenophosphate (SELP) as a selenium donor to convert the phosphoserylated transfer RNA (tRNA) for Sec (Sep-tRNASec) into Sec-tRNASec (Palioura et al. 2009, Yuan et al. 2006).
Reaction - small molecule participants:
Pi [cytosol]
H2O [cytosol]
SELP [cytosol]
Reactome.org reaction link: R-HSA-2408555
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Reaction input - small molecules:
water
selenophosphate
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-2408555