Reaction: RBP3 transports 11cRAL to rod photoreceptor outer segment
- in pathway: The canonical retinoid cycle in rods (twilight vision)
Interphotoreceptor retinoid-binding protein (RBP3) is the major soluble protein in the interphotoreceptor matrix (IPM) (Liou et al. 1989, Fong & Bridges 1988). It is thought to shuttle 11-cis-retinal (11cRAL) between retinal pigment epithelium (RPE) and photoreceptor outer segments during the visual cycle but the mechanism is poorly understood (Gonzalez-Fernandez & Ghosh 2008).
Reaction - small molecule participants:
11cRAL [cytosol]
11cRAL [cytosol]
Reactome.org reaction link: R-HSA-2454113
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Reaction input - small molecules:
11-cis-retinal
Reaction output - small molecules:
11-cis-retinal
Reactome.org link: R-HSA-2454113