Reaction: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin
- in pathway: Signaling by Activin
As inferred from mouse, upon binding Activin AB (INHBA:INHBB) or Activin B (INHBB:INHBB), the type II component of the activin receptor (ACVR2A or ACVR2B) phosphorylates the type I component ACVR1C (ALK7) at multiple serine and threonine residues within the GS domain.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-2470508
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-2470508