Reaction: Loading of acetylcholine in synaptic vesicles
- in pathway: Acetylcholine Neurotransmitter Release Cycle
Acetylcholine is actively transported from the cytosol to the lumen of the synaptic vesicle by vesicular acetylcholine transporter. Two protons are exchanged for 1 molecule of acetylcholine. The vesicular acetylcholine transporter is located in the membrane of the synaptic vesicle.
Reaction - small molecule participants:
H+ [cytosol]
H+ [clathrin-sculpted acetylcholine transport vesicle lumen]
AcCho [cytosol]
Reactome.org reaction link: R-HSA-264615
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Reaction input - small molecules:
hydron
acetylcholine
Reaction output - small molecules:
hydron
Reactome.org link: R-HSA-264615