Reaction: Cho is acetylated to AcCho by CHAT
- in pathway: Acetylcholine Neurotransmitter Release Cycle
In the cytosol, choline O-acetyltransferase (CHAT) acetylates choline (Cho) to produce acetylcholine (AcCho) (Toussaint 1992).
AcCho is synthesised in the cytoplasm of cholinergic neurons from acetyl-CoA and Cho by CHAT enzyme.
AcCho is synthesised in the cytoplasm of cholinergic neurons from acetyl-CoA and Cho by CHAT enzyme.
Reaction - small molecule participants:
AcCho [cytosol]
CoA-SH [cytosol]
Cho [cytosol]
Ac-CoA [cytosol]
AcCho [cytosol]
CoA-SH [cytosol]
Cho [cytosol]
Ac-CoA [cytosol]
Reactome.org reaction link: R-HSA-264622
======
Reaction input - small molecules:
choline
acetyl-CoA(4-)
choline
acetyl-CoA(4-)
Reaction output - small molecules:
acetylcholine
coenzyme A(4-)
acetylcholine
coenzyme A(4-)
Reactome.org link: R-HSA-264622