Reaction: Autophosphorylation of LYN kinase
- in pathway: Fc epsilon receptor (FCERI) signaling
LYN localized in lipid rafts undergoes an intermolecular autophosphorylation at tyrosine 397. This residue is present in the activation loop, and its phosphorylation promotes LYN kinase activity.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-2730862
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-2730862